A systematic review of underlying genetic factors associated with ureteropelvic junction obstruction in stenotic human tissue.

ABSTRACT:

Objective

Genetic factors are implicated in the development of ureteropelvic junction obstruction (UPJO). The aims of this study were: 1) condense and examine the existing data in studies containing information regarding differential gene expression in tissues from patients with UPJO and 2) investigate associations between genetic markers and their related pathways.

Materials and methods

A systematic review of studies published between January 2000 and September 2021 was conducted using the following databases: Ovid/Medline, PubMed, Wiley Cochrane Central Register of Controlled Trials, Web of Science, and Scopus. Of 249 studies, 10 were included in the final analysis. The search was performed using the terms "ureteropelvic junction obstruction", "genetic", "gene", and "gene

SUBMITTER: Isali I 

PROVIDER: S-EPMC10152382 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature