Treatment and Epidemiology of Third-Generation Cephalosporin-Resistant Urinary Tract Infections.

ABSTRACT:

Background and objectives

Limited data are available on the contemporary epidemiology, clinical management, and health care utilization for pediatric urinary tract infection (UTI) due to third-generation cephalosporin-resistant Enterobacterales (G3CR) in the United States. The objective is to describe the epidemiology, antimicrobial treatment and response, and health care utilization associated with G3CR UTI.

Methods

Multisite, matched cohort-control study including children with G3CR UTI versus non-G3CR UTI. UTI was defined as per American Academy of Pediatrics guidelines, and G3CR as resistance to ceftriaxone, cefotaxime, or ceftazidime. We collected data from the acute phase of illness to 6 months thereafter.

Results

Among 107 children with G3CR UTI and 206 non-G3C

SUBMITTER: Dasgupta-Tsinikas S 

PROVIDER: S-EPMC10152563 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature