Projected long-term effects of colorectal cancer screening disruptions following the COVID-19 pandemic.

ABSTRACT: The aftermath of the initial phase of the COVID-19 pandemic may contribute to the widening of disparities in colorectal cancer (CRC) outcomes due to differential disruptions to CRC screening. This comparative microsimulation analysis uses two CISNET CRC models to simulate the impact of ongoing screening disruptions induced by the COVID-19 pandemic on long-term CRC outcomes. We evaluate three channels through which screening was disrupted: delays in screening, regimen switching, and screening discontinuation. The impact of these disruptions on long-term CRC outcomes was measured by the number of life-years lost due to CRC screening disruptions compared to a scenario without any disruptions. While short-term delays in screening of 3-18 months are predicted to result in minor life-years loss,

SUBMITTER: Nascimento de Lima P 

PROVIDER: S-EPMC10154022 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature