Chemical and cytotoxicity profiles of 11 pink pepper (Schinus spp.) samples via non-targeted hyphenated high-performance thin-layer chromatography.

ABSTRACT:

Introduction

Pink pepper is a worldwide used spice that corresponds to the berries of two species, Schinus terebinthifolia Raddi or S. molle L. (Anacardiaceae). Toxic and allergic reactions by ingestion or contact with these plants were reported, and classical in vitro studies have highlighted the cytotoxic properties of apolar extracts from the fruits.

Objectives

Perform a non-targeted screening of 11 pink pepper samples for the detection and identification of individual cytotoxic substances.

Methods

After reversed-phase high-performance thin-layer chromatography (RP-HPTLC) separation of the extracts and multi-imaging (UV/Vis/FLD), cytotoxic compounds were detected by bioluminescence reduction from luciferase reporter cells (HEK 293 T-CMV-ELuc) applied directly on th

SUBMITTER: Mugge FLB 

PROVIDER: S-EPMC10154279 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature