Effects of a low-sodium diet in patients with idiopathic hyperaldosteronism: a randomized controlled trial.

ABSTRACT:

Background

Idiopathic hyperaldosteronism (IHA) is one of the most common types of primary aldosteronism (PA), an important cause of hypertension. Although high dietary sodium is a major risk factor for hypertension, there is no consensus on the recommended dietary sodium intake for IHA.

Objective

This study investigated the effect of a low-sodium diet on hemodynamic variables and relevant disease biomarkers in IHA patients, with the aim of providing a useful reference for clinical treatment.

Methods

Fifty IHA patients were evenly randomized into two groups and provided, after a 7-day run-in period (100 mmol/d sodium), either a low-sodium diet (50 mmol/d sodium) or a normal sodium diet (100 mmol/d sodium) for an additional 7 days. After the 14-day intervention (conduct

SUBMITTER: Zhou L 

PROVIDER: S-EPMC10154588 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature