Characterisation of infection-induced SARS-CoV-2 seroprevalence amongst children and adolescents in North Carolina.

ABSTRACT: Few prospective studies have documented the seropositivity among those children infected with severe acute respiratory syndrome coronavirus 2. From 2 April 2021 to 24 June 2021, we prospectively enrolled children between the ages of 2 and 17 years at three North Carolina healthcare systems. Participants received at least four at-home serological tests detecting the presence of antibodies against, but not differentiating between, the nucleocapsid or spike antigen. A total of 1,058 participants were enrolled in the study, completing 2,709 tests between 1 May 2021 and 31 October 2021. Using multilevel regression with poststratification techniques and considering our assay sensitivity and sensitivity, we estimated that the seroprevalence of infection-induced antibodies among unvaccinated child

SUBMITTER: Ahmed A 

PROVIDER: S-EPMC10154644 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature