Anti-infective characteristics of a new Carbothane ventricular assist device driveline.

ABSTRACT:

Objectives

Driveline infections are a major complication of ventricular assist device (VAD) therapy. A newly introduced Carbothane driveline has preliminarily demonstrated anti-infective potential against driveline infections. This study aimed to comprehensively assess the anti-biofilm capability of the Carbothane driveline and explore its physicochemical characteristics.

Methods

We assessed the Carbothane driveline against biofilm formation of leading microorganisms causing VAD driveline infections, including Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa and Candida albicans, using novel in vitro biofilm assays mimicking different infection micro-environments. The importance of physicochemical properties of the

SUBMITTER: Qu Y 

PROVIDER: S-EPMC10154736 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature