Surgical treatments for postamputation pain: study protocol for an international, double-blind, randomised controlled trial.

ABSTRACT:

Background

Painful conditions such as residual limb pain (RLP) and phantom limb pain (PLP) can manifest after amputation. The mechanisms underlying such postamputation pains are diverse and should be addressed accordingly. Different surgical treatment methods have shown potential for alleviating RLP due to neuroma formation - commonly known as neuroma pain - and to a lesser degree PLP. Two reconstructive surgical interventions, namely targeted muscle reinnervation (TMR) and regenerative peripheral nerve interface (RPNI), are gaining popularity in postamputation pain treatment with promising results. However, these two methods have not been directly compared in a randomised controlled trial (RCT). Here, we present a study protocol for an international, double-blind, RCT to assess th

SUBMITTER: Pettersen E 

PROVIDER: S-EPMC10155377 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature