Serum cholinesterase is associated with incident diabetic retinopathy: the Shanghai Nicheng cohort study.

ABSTRACT:

Background

Serum cholinesterase (ChE) is positively associated with incident diabetes and dyslipidemia. We aimed to investigate the relationship between ChE and the incidence of diabetic retinopathy (DR).

Methods

Based on a community-based cohort study followed for 4.6 years, 1133 participants aged 55-70 years with diabetes were analyzed. Fundus photographs were taken for each eye at both baseline and follow-up investigations. The presence and severity of DR were categorized into no DR, mild non-proliferative DR (NPDR), and referable DR (moderate NPDR or worse). Binary and multinomial logistic regression models were used to estimate the risk ratio (RR) and 95% confidence interval (CI) between ChE and DR.

Results

Among the 1133 participants, 72 (6.4%) cases of DR occur

SUBMITTER: Yu R 

PROVIDER: S-EPMC10155425 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature