Hyperoxemia in invasively ventilated COVID-19 patients-Insights from the PRoVENT-COVID study.

ABSTRACT:

Objective

We determined the prevalences of hyperoxemia and excessive oxygen use, and the epidemiology, ventilation characteristics and outcomes associated with hyperoxemia in invasively ventilated patients with coronavirus disease 2019 (COVID-19).

Methods

Post hoc analysis of a national, multicentre, observational study in 22 ICUs. Patients were classified in the first two days of invasive ventilation as 'hyperoxemic' or 'normoxemic'. The co-primary endpoints were prevalence of hyperoxemia (PaO₂ > 90 mmHg) and prevalence of excessive oxygen use (FiO₂ ≥ 60% while PaO₂ > 90 mmHg or SpO₂ > 92%). Secondary endpoints included ventilator settings and ventilation parameters, duration of ventilation, length of stay (LOS) in ICU and hospita

SUBMITTER: Tsonas AM 

PROVIDER: S-EPMC10155497 | biostudies-literature | 2024 May-Jun

REPOSITORIES: biostudies-literature