Creatinine clearance is key to solving the enigma of sex difference in in-hospital mortality after STEMI: Propensity score matching and mediation analysis.

ABSTRACT:

Background

The precise impact of sex difference on in-hospital mortality in ST-elevation myocardial infarction (STEMI) patients are unclear, and the studies are no longer consistent. Therefore, we sought to evaluate the impact of sex differences in a cohort of STEMI patients.

Methods

We analyzed the data of 2647 STEMI patients enrolled in the Kermanshah STEMI Cohort from July 2017 to May 2020. To accurately clarify the relationship between sex and hospital mortality, propensity score matching (PSM) and causal mediation analysis was applied to the selected confounder and identified intermediate variables, respectively.

Results

Before matching, the two groups differed on almost every baseline variable and in-hospital death. After matching with 30 selected variables, 574

SUBMITTER: Janjani P 

PROVIDER: S-EPMC10155957 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature