Respiratory mechanics in late COVID-19 ARDS - a restrictive pattern is strongly associated with death. A cohort study.

ABSTRACT:

Introduction

COVID-19 is associated with severe respiratory distress and high mortality. We investigated the evolution of the respiratory mechanics in COVID-19 acute respiratory distress syndrome (ARDS) and the occurrence of a restrictive respiratory pattern.

Material and methods

A retrospective, single-centre study including patients admitted to the ICU during the first wave of the pandemic (March-April 2020).

Results

A total of 141 consecutive patients were included. Many patients developed a restrictive pattern of respiratory mechanics during the course of the disease. Fifty-two patients died in the hospital (36.8%). In 29 cases (58% of the deceased) death was associated with a pattern of pulmonary mechanics, indicating a restrictive evolution of ARDS. Other diagno

SUBMITTER: Pestana D 

PROVIDER: S-EPMC10156552 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature