Lymphocyte-C-reactive protein ratio with calf circumference could better predict survival of patients with non-metastatic cancer.

ABSTRACT: Systemic inflammatory responses caused by tumor cells play an important role in the occurrence and development of tumors. The aim of this study was to identify biomarkers that most accurately predict prognoses in patients with non-metastatic cancer and to evaluate their clinical significance when combined with muscle markers. This study retrospectively evaluated 2,797 cancer patients diagnosed with cancer at TNM stages I, II, and III. Lymphocyte-C-reactive protein ratio (LCR) in conjunction with calf circumference (CC) were used (or chosed) after evaluating the predictive value of 13 inflammatory marker combinations and five anthropometric indicators for patient outcomes using the C-index. The Kaplan-Meier method and Cox's proportional hazards regression modeling were used to analyze the i

SUBMITTER: Liu XY 

PROVIDER: S-EPMC10156854 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature