Facial attractiveness is only weakly linked to genome-wide heterozygosity.

ABSTRACT:

Introduction

It has been frequently suggested that overall genomic heterozygosity and, particularly, heterozygosity of loci on the so-called major histocompatibility complex (MHC), which is responsible for the recognition of foreign substances/ pathogens and the recognition of self and non-self, is associated with better health and better resistance to infections and parasites. It has further been speculated that such a potentially beneficial heterozygosity can be detected through body odor and facial attractiveness.

Methods

On the basis of genome wide SNP data (713,014 SNPs) of participants from the Wisconsin Longitudinal Study, we therefore investigated whether homozygosity either on the MHC (measured as inbreeding coefficient) or genome-wide (measured as runs of homozygos

SUBMITTER: Fieder M 

PROVIDER: S-EPMC10157054 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature