Profiles of cognitive impairment in chronic heart failure-A cluster analytic approach.

ABSTRACT:

Background

Cognitive impairment is a major comorbidity in patients with chronic heart failure (HF) with a wide range of phenotypes. In this study, we aimed to identify and compare different clusters of cognitive deficits.

Methods

The prospective cohort study "Cognition.Matters-HF" recruited 147 chronic HF patients (aged 64.5 ± 10.8 years; 16.2% female) of any etiology. All patients underwent extensive neuropsychological testing. We performed a hierarchical cluster analysis of the cognitive domains, such as intensity of attention, visual/verbal memory, and executive function. Generated clusters were compared exploratively with respect to the results of cardiological, neurological, and neuroradiological examinations without correction for multiple testing.

Results

Dendr

SUBMITTER: Gopfert D 

PROVIDER: S-EPMC10157093 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature