Hybridization alters the gut microbial and metabolic profile concurrent with modifying intestinal functions in Tunchang pigs.

ABSTRACT:

Introduction

Hybridization has been widely used among Chinese wild boars to improve their growth performance and maintain meat quality. Most studies have focused on the genetic basis for such variation. However, the differences in the gut environment between hybrid and purebred boars, which can have significant impacts on their health and productivity, have been poorly understood.

Methods

In the current study, metagenomics was used to detect the gut microbial diversity and composition in hybrid Batun (BT, Berkshire × Tunchang) pigs and purebred Tunchang (TC) pigs. Additionally, untargeted metabolomic analysis was used to detect differences in gut metabolic pathways. Furthermore, multiple molecular experiments were conducted to demonstrate differences in intestinal functions.

SUBMITTER: He J 

PROVIDER: S-EPMC10157192 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature