New insight into the microbiome, resistome, and mobilome on the dental waste water in the context of heavy metal environment.

ABSTRACT:

Object

Hospital sewage have been associated with incorporation of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) into microbes, which is considered as a key indicator for the spread of antimicrobial resistance (AMR). The compositions of dental waste water (DWW) contain heavy metals, the evolution of AMR and its effects on the water environment in the context of heavy metal environment have not been seriously investigated. Thus, our major aims were to elucidate the evolution of AMR in DWW.

Methods

DWW samples were collected from a major dental department. The presence of microbial communities, ARGs, and MGEs in untreated and treated (by filter membrane and ozone) samples were analyzed using metagenomics and bioinformatic methods.

Results

DWW-asso

SUBMITTER: Jiao X 

PROVIDER: S-EPMC10157219 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature