Preoperative serum microRNAs as potential prognostic biomarkers in ovarian clear cell carcinoma.

ABSTRACT:

Objective

Ovarian clear cell carcinoma (OCCC) is a subtype of epithelial ovarian carcinoma with poor prognosis. However, no effective biomarkers have been established for predicting unfavorable events, including recurrence and poor prognoses. Serum microRNAs (miRNAs) have been increasingly reported to be useful in predicting a patient's condition and have been recognized as a potentially less-invasive source for liquid biopsy in cancer. Therefore, this study aimed to evaluate serum miRNA profiles from patients with OCCC and to establish biomarker for predicting the prognoses.

Methods

The GSE106817, which included preoperative serum miRNA profiles of patients with ovarian tumors, was used, and clinical information was investigated. In all, 66 patients with OCCC were included,

SUBMITTER: Suzuki K 

PROVIDER: S-EPMC10157334 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature