Role of systematic lymphadenectomy in patients with intermediate to high-risk early stage endometrial cancer.

ABSTRACT:

Objective

To determine the clinical significance of systematic lymph node dissection (LND) and to better define the relevant extent of LND in intermediate- to high-risk early stage endometrial cancer (EC).

Methods

Patients who received surgery as a primary treatment of histologically confirmed EC and preoperatively considered as uterus-confined early stage disease were included in the study population. The rates of lymph node metastasis (LNM) according to the risk groups and anatomic sites were assessed. Univariate and multivariate analyses were performed to evaluate risk factors for recurrence.

Results

A total of 804 patients were included in the study analysis. The rates of LNM were significantly different according to the risk group; 1.2% in low-risk, 20.1% in inte

SUBMITTER: Kim NR 

PROVIDER: S-EPMC10157341 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature