Risk factors for lower extremity lymphedema after surgery in cervical and endometrial cancer.

ABSTRACT:

Objective

Lower extremity lymphedema (LEL) is a well-known adverse effect related to cervical and endometrial cancer (CEC); however, very few studies have elucidated the clinicopathologic risk factors related to LEL. We investigated the incidence and risk factors in patients who received primary surgery and/or adjuvant radiotherapy (RT) or chemotherapy for CEC.

Methods

We retrospectively reviewed 2,565 patients who underwent primary surgery following CEC diagnosis between January 2007 and December 2020. LEL diagnosis was based on objective and subjective assessments by experts. We identified important predictors of LEL to construct a nomogram predicting individual risks of LEL. For internal validation of the nomogram, the original data were separated using the split-sample m

SUBMITTER: Lee J 

PROVIDER: S-EPMC10157345 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature