Association Between Intensive vs Standard Blood Pressure Control and Incident Left Ventricular Conduction Disease: A Post Hoc Analysis of the SPRINT Randomized Clinical Trial.

ABSTRACT:

Importance

Left ventricular conduction disease predicts heart failure and death, and the only strategies to mitigate its effects involve implantation of a permanent pacemaker. There are currently no proven preventive strategies for this common condition.

Objective

To determine the association between targeting intensive blood pressure (BP) control and the risk of developing left ventricular conduction disease.

Design, setting, and participants

This was a post hoc analysis of the 2-arm multicenter Systolic Blood Pressure Intervention Trial (SPRINT), which recruited participants from 102 sites in the US and Puerto Rico and was conducted from November 2010 until August 2015. Adults 50 years and older with hypertension and at least 1 other cardiovascular risk factor were

SUBMITTER: Frimodt-Moller EK 

PROVIDER: S-EPMC10157506 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature