Diet Patterns Are Associated with Circulating Metabolites and Lipid Profiles of South Asians in the United States.

ABSTRACT:

Background

South Asians are at higher risk for cardiometabolic disease than many other racial/ethnic minority groups. Diet patterns in US South Asians have unique components associated with cardiometabolic disease.

Objectives

We aimed to characterize the metabolites associated with 3 representative diet patterns.

Methods

We included 722 participants in the Mediators of Atherosclerosis in South Asians Living in America (MASALA) cohort study aged 40-84 y without known cardiovascular disease. Fasting serum specimens and diet and demographic questionnaires were collected at baseline and diet patterns previously generated through principal components analysis. LC-MS-based untargeted metabolomic and lipidomic analysis was conducted with targeted integration of known metabol

SUBMITTER: Gadgil MD 

PROVIDER: S-EPMC10157813 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature