Association between type of drinking water and upper gastrointestinal cancer incidence in the Linxian General Population.

ABSTRACT:

Background

This study aimed to explore the association between drinking water source and risk of upper gastrointestinal (UGI) cancer, including esophageal cancer (EC) and gastric cancer (GC), in the Linxian General Population Nutrition Intervention Trial (NIT) cohort.

Methods

In this study, we used data from the Linxian NIT cohort, which included 29,584 healthy adults aged 40 to 69 years. Subjects were enrolled in April 1986 and followed up until March 2016. Tap water drinking status and demographic characteristics were collected at baseline. Subjects who drank tap water were treated as the exposed group. Hazard ratios (HRs) and 95% confidence intervals (95% CIs) were estimated using the Cox proportional hazard model.

Results

A total of 5,463 cases of UGI cancer were

SUBMITTER: Yang H 

PROVIDER: S-EPMC10158328 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature