Serum metabolic profile and metabolome genome-wide association study in chicken.

ABSTRACT:

Background

Chickens provide globally important livestock products. Understanding the genetic and molecular mechanisms underpinning chicken economic traits is crucial for improving their selective breeding. Influenced by a combination of genetic and environmental factors, metabolites are the ultimate expression of physiological processes and can provide key insights into livestock economic traits. However, the serum metabolite profile and genetic architecture of the metabolome in chickens have not been well studied.

Results

Here, comprehensive metabolome detection was performed using non-targeted LC-MS/MS on serum from a chicken advanced intercross line (AIL). In total, 7,191 metabolites were used to construct a chicken serum metabolomics dataset and to comprehensively charac

SUBMITTER: Tian J 

PROVIDER: S-EPMC10158329 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature