Association of NAD⁺ levels with metabolic disease in a community-based study.

ABSTRACT:

Background

Nicotinamide adenine dinucleotide (NAD⁺) is a coenzyme and plays a crucial role in several metabolic processes. This study explored the association of nicotinamide adenine dinucleotide (NAD⁺) levels with metabolic disease (MD) in adults.

Methods

In this cross-sectional study, all data were collected from the Jidong community. MD was defined as the presence of one or more of the following disease components: hypertension, dyslipidemia, diabetes, hyperuricemia, obesity, and non-alcoholic fatty liver disease (NAFLD). The MD components were categorized into three groups: those with one component, those with two components, and those with three to six components. The whole blood NAD⁺ level was measured using a cycling assay and LC-MS/MS

SUBMITTER: Liu Y 

PROVIDER: S-EPMC10158491 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature