A bibliometric and visualized research on global trends of immune checkpoint inhibitors related complications in melanoma, 2011-2021.

ABSTRACT:

Background

Melanoma is a malignant tumor that originates from the canceration of melanocytes with a high rate of invasiveness and lethality. Immune escape has been regarded as an important mechanism for tumor development, while the treatment of immune checkpoint inhibitors (ICIs) is beneficial in restoring and enhancing the body's anti-tumor immune response to kill tumor cells. To date, ICIs therapy has achieved remarkable efficacy in treating melanoma patients. Despite the significant clinical benefits of ICIs, multiple complications such as rashes, thyroiditis, and colitis occur in melanoma patients. In this study, we aim to explore the development process and trends in the field of ICIs-related complications in melanoma, analyze current hot topics, and predict future research di

SUBMITTER: Zhang H 

PROVIDER: S-EPMC10158729 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature