Secukinumab for the treatment of generalized pustular psoriasis: A case report.

ABSTRACT:

Introduction

Generalized pustular psoriasis (GPP) is a rare subtype of psoriasis that manifests as a generalized pustular eruption.

Patient concerns

A 31-year-old female was admitted to the hospital in June 2021 with a widespread erythematous, itchy, and scaly rash for a week. The patient has a 10-year history of psoriasis vulgaris.

Diagnosis

GPP complicated by a late-stage viral infection and early-stage renal damage.

Interventions

Weekly subcutaneous injections of 300 mg of secukinumab for a month, followed by monthly (every 4 weeks) injections of 300 mg of secukinumab for 20 weeks.

Outcomes

The symptoms of pustules and erythema were reduced, and the patient reported pain relief soon after the first injection. The patient had no serious adverse reactio

SUBMITTER: Li J 

PROVIDER: S-EPMC10158903 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature