Six months survival and risk factors for attrition for patients detected with cryptococcal antigenemia through screening in Malawi.

ABSTRACT:

Main objective

A cohort of adult Malawian people living with HIV (PLHIV) testing positive for cryptococcal antigenemia was observed and followed to determine the outcomes and risk factors for attrition.

Methods concept

Eligible PLHIV were enrolled at 5 health facilities in Malawi, representing different levels of health care. ART naïve patients, ART defaulters returning to care, and patients with suspected or confirmed ART treatment failure with CD4 <200 cells/μL or clinical stage 3 or 4 were enrolled and received CrAg tests on whole blood specimens from August 2018 to August 2019. Hospitalized PLHIV were enrolled and tested for CrAg from January 2019 to August 2019, regardless of CD4 or clinical stage. Patients with cryptococcal antigenemia were managed per Malawian clinica

SUBMITTER: Chisale MRO 

PROVIDER: S-EPMC10159159 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature