Assessment of Large Animal Vascular Dimensions for Intra-Aortic Device Research and Development: A Systematic Review.

ABSTRACT: Animal studies are often required to evaluate new cardiovascular medical devices before they reach the market. Moreover, first-generation novel devices including aortic endovascular prostheses and circulatory support devices are often larger than later iterations or tested in a limited range of sizes. One of the challenges in evaluating these devices is finding a model that is both accessible and anatomically similar to humans, as there is a paucity of data on vascular dimensions in large animals. We set out to complete a comprehensive review of available reports on vascular dimensions in swine, ovine, and bovine models, with a particular focus on the descending aorta and ilio-femoral arteries. We searched Embase and MEDLINE databases for reports of descending aorta and peripheral vascular

SUBMITTER: Georges G 

PROVIDER: S-EPMC10159216 | biostudies-literature | 2023 Mar-Apr

REPOSITORIES: biostudies-literature