Associations between Per- and Polyfluoroalkyl Substances Exposures and Blood Lipid Levels among Adults-A Meta-Analysis.

ABSTRACT:

Background

Associations between per- and polyfluoroalkyl substances (PFAS) and blood lipid levels in humans were mixed.

Objectives

The objective of this meta-analysis was to summarize associations between PFAS and blood lipids in adults.

Methods

A literature search was conducted on PubMed and Web of Science for articles published through 13 May 2022 that examined associations between PFAS and blood lipids, including total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triacylglycerols (TGs). Inclusion criteria included the presence of associations between five PFAS (PFOA, PFOS, PFHxS, PFDA, and PFNA) and four blood lipid measures (TC, HDL-C, LDL-C, and TGs) in adults. Data on study characteristics and P

SUBMITTER: Liu B 

PROVIDER: S-EPMC10159273 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature