A 13-year patient journey of infant giant clival chordoma: case report and literature review.

ABSTRACT: Chordomas are rare malignant bone tumours that develop from the ectopic remnants of the embryonic notochord. In contrast to adults, the majority in children under 16 present intra-cranially (63%). In 2006, we reported the youngest case of a large clival chordoma, a 15-week old baby, the second case to present without skull base involvement and the fourth case of chordoma in a patient with tuberous sclerosis (TS) Kombogiorgas (Childs Nerv Syst 22(10):1369-1374, 2006). In this report, we provide an update on this patient's journey through a range of therapeutic options and summarize an update of the literature, since 2006, for this patient group.

SUBMITTER: Apps J 

PROVIDER: S-EPMC10159969 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature