Male reproductive traits are differentially affected by dietary macronutrient balance but unrelated to adiposity.

ABSTRACT: Dietary factors influence male reproductive function in both experimental and epidemiological studies. However, there are currently no specific dietary guidelines for male preconception health. Here, we use the Nutritional Geometry framework to examine the effects of dietary macronutrient balance on reproductive traits in C57BL/6 J male mice. Dietary effects are observed in a range of morphological, testicular and spermatozoa traits, although the relative influence of protein, fat, carbohydrate, and their interactions differ depending on the trait being examined. Interestingly, dietary fat has a positive influence on sperm motility and antioxidant capacity, differing to typical high fat diet studies where calorie content is not controlled for. Moreover, body adiposity is not significantly

SUBMITTER: Crean AJ 

PROVIDER: S-EPMC10160019 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature