The impact of pre-transplantation nephrectomy on quality of life in patients with autosomal dominant polycystic kidney disease.

ABSTRACT:

Purpose

In selected ADPKD patients, a nephrectomy is required in the work-up for a kidney transplantation. Because the impact of this procedure is unknown, we investigated the effect of pre-transplantation nephrectomy on quality of life in this group.

Methods

In this retrospective cohort study all ADPKD patients, ≥ 18 years, who received a kidney transplantation in 2 ADPKD expertise centers between January 2000 and January 2016, were asked to participate. Quality of life was assessed using three validated questionnaires on three time points. Nephrectomy was performed in preparation for transplantation.

Results

Two hundred seventy-six ADPKD patients (53 ± 9 years, 56.2% male) were included. 98 patients (35.5%) underwent native nephrectomy in preparation for transplanta

SUBMITTER: Geertsema P 

PROVIDER: S-EPMC10160200 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature