Prognostic impact and diagnostic value of invasively derived hemodynamic measures in patients with severe aortic stenosis undergoing TAVI.

ABSTRACT:

Background

Ejection time (ET), acceleration time (AT) and time between left ventricular and aortic systolic pressure peaks (T-LVAo) might be of diagnostic and prognostic use in patients with aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI).

Aim

We aimed to assess the diagnostic value and prognostic impact of invasively measured ET, AT, and T-LVAo in patients undergoing TAVI.

Methods

A total of 1274 patients received invasive measurement of ET, AT and T-LVAo prior to TAVI. Anatomic AS severity was assessed by CT-derived aortic valve calcification density (AVC_d). Impact on all-cause mortality was retrospectively analyzed.

Results

In multivariable linear regression, T-LVAo showed the strongest correlation with AVC_d

SUBMITTER: Grundmann D 

PROVIDER: S-EPMC10160203 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature