MRI as a screening tool for prostate cancer: current evidence and future challenges.

ABSTRACT:

Purpose

Prostate cancer (PCa) screening, which relies on prostate-specific antigen (PSA) testing, is a contentious topic that received negative attention due to the low sensitivity and specificity of PSA to detect clinically significant PCa. In this context, due to the higher sensitivity and specificity of magnetic resonance imaging (MRI), several trials investigate the feasibility of "MRI-only" screening approaches, and question if PSA testing may be replaced within prostate cancer screening programs.

Methods

This narrative review discusses the current literature and the outlook on the potential of MRI-based PCa screening.

Results

Several prospective randomized population-based trials are ongoing. Preliminary study results appear to favor the "MRI-only" approach. How

SUBMITTER: Wurnschimmel C 

PROVIDER: S-EPMC10160206 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature