Impact of transcatheter edge-to-edge mitral valve repair on central sleep apnoea.

ABSTRACT:

Aims

Sleep-disordered breathing (SDB) and its subtype central sleep apnoea (CSA) are highly prevalent in patients with heart failure and associated with worse prognosis. Whereas pharmacological therapy of heart failure has been shown to ameliorate CSA, results from previous studies on the effect of mitral regurgitation therapy on SDB are contradicting. The aim of this study was to assess the impact of transcatheter edge-to-edge mitral valve repair (TEER) on prevalence and severity of CSA.

Methods and results

We enrolled 47 patients undergoing TEER for symptomatic mitral regurgitation in a prospective study. Secondary mitral regurgitation and left ventricular ejection fraction < 50% were present in 79% and 68% of patients, respectively. Respiratory polygraphy was performed be

SUBMITTER: Paulus MG 

PROVIDER: S-EPMC10160214 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature