Fetal oxygenation in the last weeks of pregnancy evaluated through the umbilical cord blood gas analysis.

ABSTRACT:

Introduction

Embryo and fetus grow and mature over the first trimester of pregnancy in a dynamic hypoxic environment, where placenta development assures an increased oxygen availability. However, it is unclear whether and how oxygenation changes in the later trimesters and, more specifically, in the last weeks of pregnancy.

Methods

Observational study that evaluated the gas analysis of the umbilical cord blood collected from a cohort of healthy newborns with gestational age ≥37 weeks. Umbilical venous and arterial oxygen levels as well as fetal oxygen extraction were calculated to establish whether oxygenation level changes over the last weeks of pregnancy. In addition, fetal lactate, and carbon dioxide production were analyzed to establish whether oxygen oscillations may in

SUBMITTER: Filippi L 

PROVIDER: S-EPMC10160648 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature