IL-6 and cfDNA monitoring throughout COVID-19 hospitalization are accurate markers of its outcomes.

ABSTRACT:

Background

Severe COVID-19 entails a dysregulated immune response, most likely inflammation related to a lack of virus control. A better understanding of immune toxicity, immunosuppression balance, and COVID-19 assessments could help determine whether different clinical presentations are driven by specific types of immune responses. The progression of the immune response and tissular damage could predict outcomes and may help in the management of patients.

Methods

We collected 201 serum samples from 93 hospitalised patients classified as moderately, severely, and critically ill. We differentiated the viral, early inflammatory, and late inflammatory phases and included 72 patients with 180 samples in separate stages for longitudinal study and 55 controls. We studied selected

SUBMITTER: Bello S 

PROVIDER: S-EPMC10161166 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature