Differentiation between fetal and postnatal iron deficiency in altering brain substrates of cognitive control in pre-adolescence.

ABSTRACT:

Background

Early iron deficiency (ID) is a common risk factor for poorer neurodevelopment, limiting children's potential and contributing to global burden. However, it is unclear how early ID alters the substrate of brain functions supporting high-order cognitive abilities and whether the timing of early ID matters in terms of long-term brain development. This study aimed to examine the effects of ID during fetal or early postnatal periods on brain activities supporting proactive and reactive cognitive control in pre-adolescent children.

Methods

Participants were part of a longitudinal cohort enrolled at birth in southeastern China between December 2008 and November 2011. Between July 2019 and October 2021, 115 children aged 8-11 years were invited to participate in this neu

SUBMITTER: Hua M 

PROVIDER: S-EPMC10161450 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature