Sarcopenia provides extra value outside the PULP score for predicting mortality in older patients with perforated peptic ulcers.

ABSTRACT:

Background

Perforated peptic ulcer (PPU) remains challenging surgically due to its high mortality, especially in older individuals. Computed tomography (CT)-measured skeletal muscle mass is a effective predictor of the surgical outcomes in older patients with abdominal emergencies. The purpose of this study is to assess whether a low CT-measured skeletal muscle mass can provide extra value in predicting PPU mortality.

Methods

This retrospective study enrolled older (aged ≥ 65 years) patients who underwent PPU surgery. Cross-sectional skeletal muscle areas and densities were measured by CT at L3 and patient-height adjusted to obtain the L3 skeletal muscle gauge (SMG). Thirty-day mortality was determined with univariate, multivariate and Kaplan-Meier analysis.

Results

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SUBMITTER: Wang YH 

PROVIDER: S-EPMC10161495 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature