Interplay of gestational parent exposure to ambient air pollution and diet characteristics on preterm birth.

ABSTRACT:

Background

Despite many efforts, preterm birth (PTB) is poorly understood and remains a major public health problem in the United States. Toxicological work suggests gestational parent (GP) diet may modify the effect of ambient pollutants on birth outcomes. We assessed risk of PTB in humans in relation to fine particulate matter (PM_2.5), ozone (O₃), and nitrogen dioxide (NO₂) and variation by diet.

Methods

684 GP-singleton infant pairs in the Newborn Epigenetics Study prospective birth cohort were attributed ambient air pollutant exposures for each trimester based on residence. Total energy intake, percent of energy intake from saturated fat, and percent of energy intake from total fat were dichotomized at the 75th percentile. >We used log bi

SUBMITTER: Jardel H 

PROVIDER: S-EPMC10161541 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature