Association of serum uric acid and fasting plasma glucose with cognitive function: a cross-sectional study.

ABSTRACT:

Background

The combined effect of serum uric acid (SUA) and blood glucose on cognition has not been explored. This study aimed to examine the separate and combined association of SUA and fasting plasma glucose (FPG) or diabetes mellitus (DM) with cognition in a sample of Chinese middle-aged and elderly population.

Methods

A total of 6,509 participants aged 45 years or older who participated in the China Health and Retirement Longitudinal Study (CHARLS, 2011) were included. The three cognitive domains assessed were episodic memory, mental status, and global cognition (the sum of the first two terms). Higher scores indicated better cognition. SUA and FPG were measured. The participants were grouped based on SUA and FPG quartiles to evaluate their combined associations of cogni

SUBMITTER: Yuan Z 

PROVIDER: S-EPMC10161633 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature