Development and validation of a prediction model for unsuccessful treatment outcomes in patients with multi-drug resistance tuberculosis.

ABSTRACT:

Background

The World Health Organization has reported that the treatment success rate of multi-drug resistance tuberculosis is approximately 57% globally. Although new drugs such as bedaquiline and linezolid is likely improve the treatment outcome, there are other factors associated with unsuccessful treatment outcome. The factors associated with unsuccessful treatment outcomes have been widely examined, but only a few studies have developed prediction models. We aimed to develop and validate a simple clinical prediction model for unsuccessful treatment outcomes in patients with multi-drug resistance pulmonary tuberculosis (MDR-PTB).

Methods

This retrospective cohort study was performed between January 2017 and December 2019 at a special hospital in Xi'an, China. A total of

SUBMITTER: Ma JB 

PROVIDER: S-EPMC10161636 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature