Modelling the reopen strategy from dynamic zero-COVID in China considering the sequela and reinfection.

ABSTRACT: Although the dynamic zero-COVID policy has effectively controlled virus spread in China, China has to face challenges in balancing social-economic burdens, vaccine protection, and the management of long COVID symptoms. This study proposed a fine-grained agent-based model to simulate various strategies for transitioning from a dynamic zero-COVID policy with a case study in Shenzhen. The results indicate that a gradual transition, maintaining some restrictions, can mitigate infection outbreaks. However, the severity and duration of epidemics vary based on the strictness of the measures. In contrast, a more direct transition to reopening may lead to rapid herd immunity but necessitate preparedness for potential sequelae and reinfections. Policymakers should assess healthcare capacity for seve

SUBMITTER: Wu S 

PROVIDER: S-EPMC10161982 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature