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Accessibility of the three-year comprehensive prevention and control of brucellosis in Ningxia: a mathematical modeling study.


ABSTRACT:

Background

Brucellosis is a chronic zoonotic disease, and Ningxia is one of the high prevalence regions in China. To mitigate the spread of brucellosis, the government of Ningxia has implemented a comprehensive prevention and control plan (2022-2024). It is meaningful to quantitatively evaluate the accessibility of this strategy.

Methods

Based on the transmission characteristics of brucellosis in Ningxia, we propose a dynamical model of sheep-human-environment, which coupling with the stage structure of sheep and indirect environmental transmission. We first calculate the basic reproduction number [Formula: see text] and use the model to fit the data of human brucellosis. Then, three widely applied control strategies of brucellosis in Ningxia, that is, slaughtering of sicked

SUBMITTER: Gong W 

PROVIDER: S-EPMC10161990 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature