Breast cancer risk predictions by birth cohort and ethnicity in a population-based screening mammography program.

ABSTRACT:

Objectives

To examine whether birth cohorts affect the risk of breast cancer for East Asian, First Nations, African, South Asian and Caucasian ethnicities in British Columbia (BC).

Methods

We used Cox PH models adjusted for well-known risk factors, such as age, breast density, mammographic features on false positives, and family history, to examine risk of breast cancer among East Asian, First Nations, African and South Asian ethnicities, relative to Caucasian, across three birth cohorts.

Results

There were 813,280 participants and 11,166 in situ and invasive breast cancer diagnoses. East Asians screened in BC were found to have a lower risk of breast cancer in the birth cohort born pre-1946 compared to Caucasian, but there was no statistically significant decr

SUBMITTER: Epp J 

PROVIDER: S-EPMC10162048 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature