Syntheses, crystal structures and Hirshfeld surface analyses of four mol-ecular salts of amitriptynol.

ABSTRACT: The syntheses and crystal structures of four salts of amitriptynol (C₂₀H₂₅NO) with different carb-oxy-lic acids are described. The salts formed directly from solutions of amitriptyline (which first hydrolysed to amitriptynol) and the cor-responding acid in aceto-nitrile to form amitriptynolium [sys-tem-atic name: (3-{2-hy-droxy-tri-cy-clo[9.4.0.0^3,8]penta-deca-1(11),3,5,7,12,14-hexa-en-2-yl}pro-pyl)di-methyl-az-an-ium] 4-meth-oxy-benzoate monohydrate, C₂₀H₂₆NO⁺·C₈H₇O₃ ^-·H₂O, (I), ami-triptynolium 3,4-di-meth-oxy-benzoate trihydrate, C₂₀H₂₆NO⁺·C₉H₉O₄ ^-·3H₂O, (II), amitrip

SUBMITTER: Vinaya 

PROVIDER: S-EPMC10162082 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature