Research progress of extracellular vesicles as biomarkers in immunotherapy for non-small cell lung cancer.

ABSTRACT: Lung cancer is one of the most severe forms of malignancy and a leading cause of cancer-related death worldwide, of which non-small cell lung cancer (NSCLC) is the most primary type observed in the clinic. NSCLC is mainly treated with surgery, radiotherapy, and chemotherapy. Additionally, targeted therapy and immunotherapy have also shown promising results. Several immunotherapies, including immune checkpoint inhibitors, have been developed for clinical use and have benefited patients with NSCLC. However, immunotherapy faces several challenges like poor response and unknown effective population. It is essential to identify novel predictive markers to further advance precision immunotherapy for NSCLC. Extracellular vesicles (EVs) present an important research direction. In this review, we f

SUBMITTER: Ge Y 

PROVIDER: S-EPMC10162406 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature