Automated control for investigation of the insufflation-ventilation interaction in experimental laparoscopy.

ABSTRACT: In laparoscopic surgery the abdominal cavity is insufflated with pressurized carbon dioxide gas to create workspace. This pressure is exerted through the diaphragm onto the lungs, competing with ventilation and hampering it. In clinical practice the difficulty of optimizing this balance can lead to the application of harmfully high pressures. This study set out to create a research platform for the investigation of the complex interaction between insufflation and ventilation in an animal model. The research platform was constructed to incorporate insufflation, ventilation and relevant hemodynamic monitoring devices, controlling insufflation and ventilation from a central computer. The core of the applied methodology is the fixation of physiological parameters by applying closed-loop contro

SUBMITTER: van Weteringen W 

PROVIDER: S-EPMC10162516 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature