Analyzing the sensitivity of quantitative 3D MRI of longitudinal relaxation at very low field in Gd-doped phantoms.

ABSTRACT:

Purpose

Recently, new MRI systems working at magnetic field below 10 mT (Very and Ultra Low Field regime) have been developed, showing improved T1-contrast in projected 2D maps (i.e. images without slice selection). Moving from projected 2D to 3D maps is not trivial due to the low SNR of such devices. This work aimed to demonstrate the ability and the sensitivity of a VLF-MRI scanner operating at 8.9 mT in quantitatively obtaining 3D longitudinal relaxation rate (R1) maps and distinguishing between voxels intensities. We used phantoms consisting of vessels doped with different Gadolinium (Gd)-based Contrast Agent (CA) concentrations, providing a set of various R1 values. As CA, we used a commercial compound (MultiHance®, gadobenate dimeglumine) routinely used in clinical MRI.

Me

SUBMITTER: de Iure D 

PROVIDER: S-EPMC10162526 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature